Primary Identifier | MGI:2387116 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Dct |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129/Sv | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Exon 1, which is the first coding exon, was replaced with a cassette containing cre and neo. RT-PCR indicated an absence of normal transcript in homozygous mice. Normal protein was undetected by Western blot analysis of skin extracts and by immunohistochemical analysis of embryonic retinal pigment epithelium. |