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Allele : Dct<tm1(cre)Bee> dopachrome tautomerase; targeted mutation 1, Friedrich Beermann
Primary Identifier  MGI:2387116 Allele Type  Targeted
Attribute String  Recombinase Gene  Dct
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129/Sv Is Recombinase  true
Is Wild Type  false
molecularNote  Exon 1, which is the first coding exon, was replaced with a cassette containing cre and neo. RT-PCR indicated an absence of normal transcript in homozygous mice. Normal protein was undetected by Western blot analysis of skin extracts and by immunohistochemical analysis of embryonic retinal pigment epithelium.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Dct <-> KO,
  • Dct<Cre>,
  • Dct<->,
  • Dct<->,
  • Dct<Cre>,
  • Dct <-> KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

15 Publication categories





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