Primary Identifier | MGI:2387330 | Allele Type | Spontaneous |
Attribute String | Modified regulatory region | Gene | Foxe3 |
Inheritance Mode | Recessive | Strain of Origin | SJL/J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Mice exhibit a spontaneous deletion of 22 bp in a highly conserved region upstream of the gene in a major lens regulatory element. RT-PCR analysis of eye extracts confirmed reduced transcript expression. |