Primary Identifier | MGI:2387336 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Usp18 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2-4, which contain the translation initiation codon and Cys domain, were replaced with a neo-lacZ cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of LPS-stimulated thymus glands. |