| Primary Identifier | MGI:2387343 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | G6pc1 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 3 was replaced with a neomycin selection cassette via homologous recombination. Neither transcript nor protein were detected in homozygous mutant mice by a protection assay and Western blot analysis of liver and kidney tissues. Functional ablation was confirmed by the absence of glucose-6-phosphate hydrolysis in liver and kidney microsomes obtained from homozygous mutant mice. |
