Primary Identifier | MGI:2387562 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Pdx1-cre)1Herr |
Strain of Origin | (C57BL/6J x CBA/J)F2 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The 4.5 kb region containing Pdx1 regulatory sequences was used to drive expression of a cre recombinase constructed modified with a nuclear localization signal upstream of a human hGH minigene. The Pdx1 promoter drives expression in the pancreas. Mosaic cre expression is first observed in the pancreatic epithelium at E11.5. Expression continues to be mosaic at E12.5. |