Primary Identifier | MGI:2387797 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tnfrsf17 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exon 3 with a neomycin resistance cassette via homologous recombination. The mutation deletes amino acids 119-143 which includes most of the intracellular domain, a region involved in binding TNF receptor-associated factors. |