| Primary Identifier | MGI:2387813 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sftpc |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = D3R. |
| molecularNote | The gene was disrupted by insertion of a PGK-neo cassette into exon 2. No mature mRNA was detected in homozygous mutant animals via Northern blot of lung tissue, but a faint band of smaller size was observed. RT-PCR and sequence analysis revealed the product was an alternatively spliced transcript from exon 1 to exon 3, bypassing exon 2. No protein product was detected in alveolar lavage from homozygous mutant animals. |
