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Allele : Il6st<tm2Thir> interleukin 6 signal transducer; targeted mutation 2, Toshio Hirano

Primary Identifier  MGI:2386993 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Il6st
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A human Il6st cDNA fragment carrying tyrosine to phenylalanine substitutions at amino acids 767, 814, 905, and 915, was used to replaced the corresponding region of the mouse gene. A downstream neomycin resistance cassette was also inserted for positive selection.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • gp130<FXXQ>,
  • gp130<FXXQ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele