| Primary Identifier | MGI:2387417 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(CAG-CCND1)1Tera |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct consisted of a CAG promoter (chicken beta actin promoter and CMVIE enhancer) followed by a floxed neo-polyA region upstream of the human CCND1 coding region. CCND1 expression under the control of the CAG promoter only occurs after cre excision of the floxed neo-polyA cassette. Five transgenic founder lines were produced. Cre mediated recombinations were confirmed in three lines, two carrying five copies of the transgene and one carrying 10 copies. This line has five copies and was stably transmitted to the next generation. |
