| Primary Identifier | MGI:2387662 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cdk5r2 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette in the reverse orientation replaced 1 kb of the coding region resulting in deletion of amino acids 1-346 and 100 bp of upstream noncoding sequences. Absence of gene expression in homozygous animals was demonstrated by Western blot analysis of whole brain lysates. Histone 1 kinase activity is also absent in brain lysates of homozygous mutant animals. |
