Primary Identifier | MGI:2387684 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Prnp)1Co |
Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Cosmid clone cos.6I/LnJ-4 carrying mouse gene Prnp was used for the transgene. The cosmid Prnp sequence is derived from inbred strain I/LnJ, which carries the Prnpb allele (valine residue at position 189). Expression of the transgene was verified by RT-PCR analysis of transgenic animals. |