| Primary Identifier | MGI:2387694 | Allele Type | Targeted |
| Gene | Cdkn1b | Transmission | Germline |
| Strain of Origin | 129S4/SvJaeSor | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The gene was replaced with a construct composed of a loxP-flanked stop box element within the promoter region and a gene carrying a threonine to alanine substitution at position 187 (T187A). The lox-STOP-lox element was removed by breeding homozygous animals to a line expressing cre recombinase constitutively in the germ line thereby allowing expression of the mutant allele in the next generation. |
