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Allele : Omp<tm1Flm> olfactory marker protein; targeted mutation 1, Frank L Margolis

Primary Identifier  MGI:2387862 Allele Type  Targeted
Attribute String  Null/knockout Gene  Omp
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region of the endogenous locus was replaced with a neomycin selection cassette inserted by homologous recombination. Western blot analysis of homozygous mutant mice showed an absence of protein in olfactory epithelium and olfactory bulbs. ELISA showed the protein level in heterozygous mice to be 40-50% of that in wild-type mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories