Primary Identifier | MGI:2387400 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tcf12 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The insertion of a neomycin selection cassette deleted sequence encoding the 3' portion of the basic helix-loop-helix (bHLH) domain. The disruption of the bHLH precludes dimerization, thereby preventing the potential for DNA binding activity. |