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Allele : Mertk<tm1Grl> MER proto-oncogene tyrosine kinase; targeted mutation 1, Greg Lemke

Primary Identifier  MGI:2387765 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mertk
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exon 18 of the gene, which encodes part of the kinase domain known to be essential for tyrosine kinase function. An RNase protection assay demonstrated that a mutant transcript was expressed that lacked the deleted sequences.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mer<->,
  • Mer<->,
  • Mertk<->,
  • Mertk<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

97 Publication categories