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Allele : Mertk<tm1Gkm> MER proto-oncogene tyrosine kinase; targeted mutation 1, Glenn K Matsushima

Primary Identifier  MGI:2387768 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mertk
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced sequences including the last exon, which encodes the carboxy terminal end of the kinase domain and the cytoplasmic tail. RT-PCR analysis demonstrated that a mutant transcript was expressed from this allele that lacked sequences encoding the cytoplasmic kinase domain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • MERKO,
  • Mer<->,
  • Mertk<-/-V1>,
  • Mertk<-/-V1>,
  • mertk<kd>,
  • mertk<kd>,
  • Mer<->,
  • mer<kd>,
  • MERKO,
  • mer<kd>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

52 Publication categories