|  Help  |  About  |  Contact Us

Allele : Kcnc2<tm1Rudy> potassium voltage gated channel, Shaw-related subfamily, member 2; targeted mutation 1, Bernardo Rudy

Primary Identifier  MGI:2387957 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnc2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3' portion of exon 1, encoding the tetramerization domain (T domain) involved in oligomerization of potassium voltage gated channel subunits, was replaced by a neomycin selection cassette inserted by homologous recombination. Neither transcript nor protein was detected by Northern and Western blot analyses of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Kv3.2 -,
  • Kv3.2 -
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories