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Allele : Ltbp4<Gt(U3Cre)1Vmel> latent transforming growth factor beta binding protein 4; gene trap 1, Harald von Melchner

Primary Identifier  MGI:2388061 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Ltbp4
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A retroviral gene trap vector, containing cre recombinase and U3 sequences, integrated into intron 5 in a reverse transcriptional orientation. A 98% reduction in mRNA levels was identified in homozygous mutant mice by Northern blot analysis. Western blot analysis results were correlative. The insertion of the vector is thought to interfere with the splicing of this gene.
  • mutations:
  • Insertion of gene trap vector
  • cellLines:
  • 3C7
  • synonyms:
  • 3C7,
  • Ltbp4S<->,
  • Ltbp4S<->,
  • 3C7
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

18 Publication categories