| Primary Identifier | MGI:2388160 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Vax2 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was replaced by a neo cassette inserted by homologous recombination. RT-PCR analysis identified shortened transcript in homozygous mutant mice, lacking the targeted region, which encoded the first two alpha helices (residues 83 through 145) of the homeodomain. A loss of immunoreactivity was observed in the homozygous mutant retina. |
