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Allele : Folh1<tm1Nle> folate hydrolase 1; targeted mutation 1, Joseph H Neale

Primary Identifier  MGI:2388359 Allele Type  Targeted
Attribute String  Null/knockout Gene  Folh1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The endogenous locus was disrupted by the insertion of a vector that replaced the 3' and 5' splice sites of exons 1 and 2, respectively, with sequence containing stop codons. The targeting vector also included a neo cassette that replaced the majority of intron 1. Neither transcript nor protein was detected by Northern or Western blot analyses of brain tissue obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Folh1<->,
  • Folh1<tm1ski>,
  • Folh1<tm1ski>,
  • PMSA<->,
  • Folh1<->,
  • PMSA<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele