| Primary Identifier | MGI:2388369 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hoxb4 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = R1-45, a subline of R1. |
| molecularNote | This allele is derived from Hoxb4tm2Nrm. Embryos from heterozygous Hoxb4tm2Nrm intercrosses were injected with a cre expression plasmid to remove the floxed neo cassette in the first coding exon. The deletion leaves behind a 78 bp insertion containing a loxP site in the first exon. The 78 bp insertion contains a stop codon in-frame with the Hoxb4 transcript. |
