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Allele : Pdx1<tm1Macd> pancreatic and duodenal homeobox 1; targeted mutation 1, Raymond J MacDonald
Primary Identifier  MGI:2388676 Allele Type  Targeted
Attribute String  Transactivator Gene  Pdx1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2, which encompass the entire coding region, were replaced with a cassette containing a tetracycline transactivator (tTA) and a neo resistance gene. RT-PCR showed tTA expression in adult pancreas tissue but not in other visceral organs or salivary glands.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pdx1<tTA>,
  • Pdx1<tTA>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

30 Publication categories





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