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Allele : Drd2<tm1Ebo> dopamine receptor D2; targeted mutation 1, Emiliana Borrelli

Primary Identifier  MGI:2387895 Allele Type  Targeted
Attribute String  Null/knockout Gene  Drd2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2, which contains the translational start codon, was replaced by a neomycin selection cassette inserted by homologous recombination. Transcript was undetected in homozygous mutant mice by Northern blot analysis of RNA isolated from striata. An absence of functional protein was determined by radiolabeled ligand binding analyses.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • D2R<->,
  • D2R<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

38 Publication categories