Primary Identifier | MGI:2388010 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Il17a |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1 and 2 were replaced with a cassette containing an EGFP gene followed by a floxed neomycin resistance gene. Transcript was undetected by Northern blot analysis of stimulated splenic T cells derived from homozygous mutant mice. The absence of protein in T cell supernatent was determined by ELISA. |