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Allele : Tnfsf10<tm1Sdg> tumor necrosis factor (ligand) superfamily, member 10; targeted mutation 1, Lisa M Sedger

Primary Identifier  MGI:2388390 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnfsf10
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A portion of exon 2 and all of exon 3 were replaced by a neomycin selection cassette inserted by homologous recombination. Splicing of untargeted exons results in a frameshift mutation. Truncated transcript was detected by RT-PCR analysis of RNA obtained from homozygous mutant splenocytes. A premature stop codon was identified by sequence analyis of this transcript.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • TRAIL<->,
  • TRAIL<->,
  • TRAIL-Apo2L<->,
  • TRAIL-Apo2L<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

32 Publication categories