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Allele : Mllt3<tm1.1Thr> myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3; targeted mutation 1.1, Terence H Rabbitts

Primary Identifier  MGI:2388982 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mllt3
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  The second coding exon of the endogenous gene was disrupted by homologous recombination of a construct containing IRES-lacZ and a floxed neo gene and subsequent excision of the selection cassette. A single loxP site was left downstream of the lacZ reporter, which was expressed via the endogenous promoter. RT-PCR analysis of homozygous mutant mice showed a lack of normal transcript.
  • mutations:
  • Insertion
  • synonyms:
  • Af9NO,
  • Af9<->,
  • Af9<->,
  • Af9NO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories