Primary Identifier | MGI:2389369 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(H2-K-TYROBP)11Viv |
Strain of Origin | (C57BL/6 x CBA/J)F2 | Is Recombinase | false |
Is Wild Type | false |
description | The transgenic construct was injected into fertilized eggs obtained from an F2 cross of C57BL/6 (H-2b) and CBA/J(H-2k). |
molecularNote | Human TYROBP cDNA sequence was adjoined to the MHC class I promoter/immunoglobulin enhancer. Founder mice carried 11 copies of the the transgenic construct. Expression was detected in splenocytes by Western blot analysis and on all splenic myeloid and lymphoid cells by flow cytometric analysis. |