| Primary Identifier | MGI:2388704 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Trp53 |
| Transmission | Chimeric | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacment of exons 2-10 with a neo-TK cassette via homologous recombination. Germline founder animals were established but did not transmit the mutant allele to offspring, indicating a 100% segregation distortion. Authors hypothesize the HSV-TK gene is responsible for the lack of allele transmission. |
