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Allele : Afp<tm1Ibmm> alpha fetoprotein; targeted mutation 1, Claude Szpirer

Primary Identifier  MGI:2388722 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Afp
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A portion of exon 1 and all of exons 2 and 3 were replaced by a cassette containing both lacZ and neo. The insertion was designed to delete the 3' promoter (in intron 1) and leave lacZ under the control of the 5' promoter located upstream of exon 1. Beta-galactosidase expression was verfied by staining. The absence of endogenous transcript and protein was confirmed by Northern and Western blot analyses.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories