| Primary Identifier | MGI:2388722 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Afp |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A portion of exon 1 and all of exons 2 and 3 were replaced by a cassette containing both lacZ and neo. The insertion was designed to delete the 3' promoter (in intron 1) and leave lacZ under the control of the 5' promoter located upstream of exon 1. Beta-galactosidase expression was verfied by staining. The absence of endogenous transcript and protein was confirmed by Northern and Western blot analyses. |