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Allele : Nfatc4<tm1Jmk> nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4; targeted mutation 1, Jeffery D Molkentin

Primary Identifier  MGI:2388915 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfatc4
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 through 5 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the Rel homology domain. Neither transcript nor protein was detected in cardiac tissue obtained from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele