| Primary Identifier | MGI:2389104 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(KRT5-Ccnd3)2203Mlrp |
| Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Murine Ccnd3 cDNA sequence preceded by a beta-globin intron was ligated to 5.2 kb of bovine KRT5 regulatory sequence. The KRT5 promoter directed expression in basal cells of squamous stratified epithelia. Expression of the transgenic protein was detected by Western blot analysis of epidermal tissue. Quantification of the Western blot results indicated a nearly 5.5-fold increase relative to wild-type samples. |
