Primary Identifier | MGI:2388945 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Ctns |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The endogenous allele was disrupted by the insertion of a construct containing an IRES linked beta-geo cassette. Normal transcript was undetected in homozygous mutant mice by Northern blot analysis. The absence of functional protein was indicated by the observation of incorrect localization and a lack of cystine transport activity. |