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Allele : Ctns<tm1Antc> cystinosis, nephropathic; targeted mutation 1, Corinne Antignac

Primary Identifier  MGI:2388945 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ctns
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  The endogenous allele was disrupted by the insertion of a construct containing an IRES linked beta-geo cassette. Normal transcript was undetected in homozygous mutant mice by Northern blot analysis. The absence of functional protein was indicated by the observation of incorrect localization and a lack of cystine transport activity.
  • mutations:
  • Insertion
  • synonyms:
  • Ctns-,
  • Ctns-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

30 Publication categories

Trail: Allele