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Allele : Scn8a<dmu> sodium channel, voltage-gated, type VIII, alpha; degenerating muscle

Primary Identifier  MGI:2429654 Allele Type  Spontaneous
Gene  Scn8a Inheritance Mode  Recessive
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Genetic complementation testing between the dmu mouse and Scn8amed mice demonstrated that these two mutations are allelic. Transcript levels from this gene are greatly reduced in homozygous mice. This mutant contains a single nucleotide deletion in exon 10A (position 1538 in GenBank NM_011323).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • dmu,
  • dmu
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories