| Primary Identifier | MGI:2389272 | Allele Type | Targeted |
| Gene | Camk2a | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Sequence encoding threonine 305 was targeted by homologous recombination of a construct containing an engineered arginine substitution mutation. The replacement of the this threonine residue with the negatively charged argnine was designed to interfere with calcium/calmodulin binding. Western blot analysis confirmed the expression of a normal sized protein. A single loxP site was left within the locus. |
