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Allele : Fah<tm1Mgo> fumarylacetoacetate hydrolase; targeted mutation 1, Markus Grompe

Primary Identifier  MGI:2429529 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fah
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5 was disrupted by the insertion of a neomycin selection cassette. A biochemical assay of liver tissue showed fumarylacetoacetate hydrolase activity to be reduced by approximately 50% in heterozygous mice and completely ablated in homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • Fah<deltaexon5>-1,
  • Fah<Dexon5>,
  • Fah-,
  • Fah<Dexon5>,
  • Fah-,
  • Fah<deltaexon5>-1
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

64 Publication categories