| Primary Identifier | MGI:2429971 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nr4a2 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 3 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded amino acids 1 through 288, encompassing the initiating methionine and the first zinc finger domain. Transcript lacking exon 3 was detected in mutant mice by Northern blot analysis of brain tissue. Normal transcript was undetected in the substantia nigra and ventral tegmental area by in situ hybridization. |
