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Allele : Ccnb1<tm1Thnt> cyclin B1; targeted mutation 1, Tim Hunt

Primary Identifier	MGI:2429976	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Ccnb1
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Sequence extending from within exon 5 into exon 9 was replaced by a Beta-geo cassette inserted by homologous recombination. The deleted region included the cyclin box which is involved in the binding of cell cycle division 2.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Brandeis M, et al. (1998) Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero. Proc Natl Acad Sci U S A 95(8):4344-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

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