| Primary Identifier | MGI:2429747 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Ttr-Cdkn1a)36Tvd |
| Strain of Origin | (C57BL/6 x DBA/2)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct contained murine Cdkn1a cDNA sequence adjoined to murine transthyretin (Ttr) sequence including 3 kb of the upstream regulatory region, exon 1, intron 1, and a portion of exon 2. Both the endogenous start codon and an additional ATG in exon 2 of Ttr were converted to restriction sites by site-directed mutagenesis. The Ttr regulatory region directs expression in the liver. |
