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Protein Coding Gene : Egfbp2 epidermal growth factor binding protein type B
Primary Identifier  MGI:95292 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  13647
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables peptidase activity. Acts upstream of or within zymogen activation. Located in extracellular space. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).
specificity  Blast analyses suggest that this gene is missing from the current reference (GRCm38, based on C57BL/6J genome) and alternate Celera (based on mixed strain genomes) assemblies. Therefore, the RefSeq for this locus was based on sequence from the ICR strain, which has been reported in literature to contain both genes.
  • synonyms:
  • epidermal growth factor binding protein type B,
  • Egfbp2,
  • Egfbp-2,
  • MGD-MRK-9320,
  • MGD-MRK-9317
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Features --> Cross References

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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