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QTL : Lpn2 NZ lupus nephritis 2
Primary Identifier  MGI:96822 Organism  mouse, laboratory
Chromosome  17 Mgi Type  QTL
description  PHENOTYPE: NZB and NZW do not develop lupus nephritis, but F1 progeny and backcrosses to parental strains do. Combined dominant alleles at Lpn1, Lpn2 and Lpn3 determine disease susceptibility. NZW alleles are dominant for Lpn2 and Lpn3 and recessive for Lpn1. Lpn2 may be identical or related to Ads3 and Agp3. [provided by MGI curators]
  • synonyms:
  • Lpn2,
  • NZ lupus nephritis 2,
  • MGD-MRK-11876,
  • MGD-MRK-11873,
  • LN-2,
  • Lpn-2,
  • MGD-MRK-11836,
  • lupus nephritis 2
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