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QTL : Lus lymphoid cytostasis suppressor

Primary Identifier	MGI:96852	Organism	mouse, laboratory
Chromosome	UN	Mgi Type	QTL

description

PHENOTYPE: Lus induces sensitization of T- and B-cells that cause cytostasis of target tumor cells. The dominant B10.D2 allele suppresses production of the effector cells; the BALB/c allele enhances production. Lus interacts with an Arp mutant to produce an autoimmune lymphoid/erythroid hyperplastic disorder. [provided by MGI curators]

synonyms:
MGD-MRK-11930,
lymphoid cytostasis suppressor,
Lus

earliestPublication:
De Giorgi L, et al. (1979) Modification of the anti-tumour immune response by suppressor gene products of lymphoid cells. Immunology 36(4):711-8

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Involved In Mutations

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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QTL : Lus lymphoid cytostasis suppressor

External Links

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Involved In Mutations

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Function

Mouse features --> Functions (GO terms)

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

Other

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