| Primary Identifier | MGI:2441657 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Slc4a1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin selection cassette was inserted into exon 3. The insertion disrupted the coding region 12 codons downstream of the erythroid-specific start codon. While no protein was detected in red blood cells obtained from homozygous mutant mice, translation of the kidney specific isoform, which is initiated from a start codon downstream of the inserted neo cassette, was verified by Western blot analysis of kidney lysates. |