Primary Identifier | MGI:2445451 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Yy1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A genomic fragment containing exon 1 and the proximal promoter region was replaced with a neomycin selection cassette via homologous recombination. The deleted region encoded 227 of the 414 amino acids in the endogenous protein. No protein was detected in homozygous mutant embryos by immunostaining. |