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Allele : Rarg<tm4Ipc> retinoic acid receptor, gamma; targeted mutation 4, Pierre Chambon

Primary Identifier  MGI:2445724 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rarg
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  An isoform specific disruption was achieved by the insertion of a promoterless neomycin selection cassette into exon 3 via homologous recombination. Whereas gamma1 transcript was undetected by RT-PCR analysis of homozygous mutant mice, gamma2 mRNA was readily amplified. An RNAse protection assay further indicated the absence of the gamma1 isoform.
  • mutations:
  • Insertion
  • synonyms:
  • RARgamma1<->,
  • RARgamma1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories