| Primary Identifier | MGI:2445746 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mybl2 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 5, which encodes amino acids 94 through 167, was replaced by the insertion of a neomycin selection cassette. The deleted region encompassed portions of repeats 2 and 3 that are involved in DNA binding. Whereas this allele was observed to be homozygously lethal, similar amounts of protein were detected by Western blot analysis of wild-type and heterozygous mice. |
