| Primary Identifier | MGI:2446069 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(BGLAP-cre)1Clem |
| Strain of Origin | FVB/NJ | Is Recombinase | true |
| Is Wild Type | false |
| description | Two transgenic lines, designated 4 and 6, were established. |
| molecularNote | A human osteocalcin (BGLAP) promoter, driving expression in osteoblasts, fused to a cre recombinase gene was used for the transgene. The cre gene was modified to include a nuclear localization signal and human ACTB 3' untranslated region. Two lines were generated, 4 and 6. This allele represents line 6. Transgene expression was observed in the calvaria, femur, and vertebrae by Northern blot analysis. |
