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Allele : Tg(Sap-Mgat3)1Nta transgene insertion 1, Naoyuki Taniguchi

Primary Identifier  MGI:2445494 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Sap-Mgat3)1Nta
Is Recombinase  false Is Wild Type  false
description  Two transgenic founders were created, SAP-1 (4 copies of transgene) and SAP-2 (6 copies of transgene). Transgene expression and enzyme activity levels correlate to the number of copies present, with higher expression and activity in SAP-2 compared to SAP-1.
molecularNote  A rat Mgat3 cDNA sequence fused to the Apcs promoter was used for the transgene. Transgene expression was confirmed by Northern blot analysis of livers RNA from transgenic animals.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories