Primary Identifier | MGI:2445494 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Sap-Mgat3)1Nta |
Is Recombinase | false | Is Wild Type | false |
description | Two transgenic founders were created, SAP-1 (4 copies of transgene) and SAP-2 (6 copies of transgene). Transgene expression and enzyme activity levels correlate to the number of copies present, with higher expression and activity in SAP-2 compared to SAP-1. |
molecularNote | A rat Mgat3 cDNA sequence fused to the Apcs promoter was used for the transgene. Transgene expression was confirmed by Northern blot analysis of livers RNA from transgenic animals. |